As a result of the Response to Intervention (RTI) mandate in schools across many states, school counselors are well-positioned to take a leadership role. The present research study examines how school counselors across the nation perceived their training and knowledge of RTI, as well as their confidence in its implementation. Results indicate that while the majority of school counselors reported positive beliefs about RTI, they had limited confidence in their preparedness to perform certain RTI-related responsibilities, including collecting and analyzing data to determine intervention effectiveness and collaboration through teamwork. These perceived areas of deficiency point to a significant discrepancy with the American School Counselor Association National Model’s components and themes. Through building skills and capacity for leadership, school counselors can spearhead schoolwide teams to create and evaluate the effectiveness of culturally relevant and evidence-based interventions. School counselors and school counselor educators must use a multi-tiered system of supports as an opportunity to advance the field.